Small-molecule switches put therapeutic CRISPR editing under on-demand control in living tissues
In a study published in Science Translational Medicine, a team of researchers led by Dr. Wang Yu from the Shenzhen Institutes of Advanced Technology of the Chinese Academy of Sciences developed PRINCE and Little Prince, dual small-molecule-controlled genome editing systems that allow CRISPR activity to be switched on by drug inducers and kept largely silent in their absence.
The science section covers breakthroughs in medicine, physics, biology, and technology. We surface discoveries that expand what humanity can do, from new treatments reaching clinical trials to engineering feats that seemed impossible a decade ago. Every link goes to the original publisher so you can read the full study or press release yourself.
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