Engineering enzymes with potential against ALS and Parkinson's disease
In an advance that could one day lead to new treatments for neurodegenerative diseases, Meredith Jackrel, an associate professor of chemistry in Arts & Sciences at Washington University in St. Louis, and her team have developed a method to rapidly produce and screen a class of disaggregase enzymes that can break down the misfolded proteins associated with ALS and Parkinson's disease.
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